論文など

2022

西角光平, 稲永敏明, 西明仁, 米澤隆弘, 野口龍生, 鳥居恭司, 今川和彦, 小林朋子*. 褐毛和種におけるBoLA-DRB3遺伝子の多様性解析. 獣医疫学雑誌 26(2) in press

Nishikaku K, Yonezawa T, Nishibori M, Harada M, Kawaguchi F, Sasazaki S, Torii Y, Imakawa K, Kawai K, Liu J, Mannen H and Kobayashi T*. Phylogenomics and Spatiotemporal Dynamics of Bovine Leukemia Virus (BLV) Focusing on Asian Native Cattle: Insights Into the Early Origin and Global Dissemination. Frontiers in Microbiology 13:917324

Nishikaku K, Noguchi T, Murakami S, Torii Y and Kobayashi T*. Molecular analysis of bovine leukemia virus in early epidemic phase in Japan using archived formalin fixed paraffin embedded histopathological specimens. The Journal of Veterinary Medical Science 84(3): 350-357

2021

Ohnuki N, Kobayashi T, Matsuo M, Nishikaku K, Kusamam K, Torii Y, Inagaki Y, Hori M, Imakawa K and Satou Y. A target enrichment high through-put sequencing system for characterization of BLV whole genome sequence, integration sites, clonality and host SNP. Scientific Reports 11:4521. (†: equal contribution)

西角光平, 小林朋子*. 日本における牛白血病の発生と拡散の歴史. 日本獣医史学雑誌 58:1-8

2020

Inagaki Y, Kobayashi T, Suda Y, Kusama K and Imakawa K. Genetic variation in Japanese Holstein cattle for EBL development. BMC veterinary research  16, 407 https://doi.org/10.1186/s12917-020-02625-8

2019

Nishikaku K, Ishikura R, Ohnuki N, Polat M, Aida Y, Murakami S, Kobayashi T*. Broadly applicable PCR restriction fragment length polymorphism method for genotyping bovine leukemia virus. J Vet Med Sci. (*: corresponding author)

Kobayashi T, Inagaki Y, Ohnuki N, Sato R, Murakami S, Imakawa K. Increasing Bovine leukemia virus (BLV) proviral load is a risk factor for progression of Enzootic bovine leucosis: A prospective study in Japan. Prev Vet Med

2018

Konno Y, Nagaoka S, Kimura I, Ueda MT, Kumata R, Ito J, Nakagawa S, Kobayashi T, Koyanagi Y, Sato K. A naturally occurring feline APOBEC3 variant that loses anti-lentiviral activity by lacking two amino acid residues. J Gen Virol 99(5):704-709

Konno Y, Nagaoka S, Kimura I, Yamamoto K, Kagawa Y, Kumata R, Aso H, Ueda MT, Nakagawa S, Kobayashi T, Koyanagi Y, Sato K. New World feline APOBEC3 potently controls inter-genus lentiviral transmission. Retrovirology 10;15(1):31

2017

稲垣靖子, 小林朋子, 須田義人, 今川和彦. 牛個体識別番号を利用した牛白血病の疫学的解析と家畜育種学的アプローチ. 畜産の研究 71:(11)917-924

大貫永輝, 村上覚史, 小林朋子*. ダイレクトPCR法による腫瘍組織からの牛白血病ウイルス遺伝子の検出. 山口獣医学雑誌 44 号9-18

2016

Yoshikawa R, Izumi T, Nakano Y ,Yamada E, Moriwaki M, Misawa N, Ren F, Kobayashi T, Koyanagi Y, Sato K. Small ruminant lentiviral Vif proteins commonly utilize cyclophilin A, an evolutionarily and structurally conserved protein, to degrade ovine and caprine APOBEC3 proteins. Microbiol Immunol 60;6:427-36.

Yamada E,Yoshikawa R, Nakano Y, Misawa N, Kobayashi T, Ren F, Izumi T, Miyazawa T, Koyanagi Y, and Sato K. A naturally occurring bovine APOBEC3 confers resistance to bovine lentiviruses: implication for the co-evolution of bovids and their lentiviruses. Scientific Reports 26;6:33988. PubMed

Matsuu A, Kobayashi T, Patchimasiri T, Shiina T, Suzuki S, Chaichoune K, Ratanakorn P, Hiromoto Y, Abe H, Parchariyanon S, Saito T. Pathogenicity of Genetically Similar, H5N1 Highly Pathogenic Avian Influenza Virus Strains in Chicken and the Differences in Sensitivity among Different Chicken Breeds. PLoS One   11 ( 4 ) e0153649

小林朋子, 綿貫園子, 菊池柚衣, 竹嶋伸之輔, 間陽子, 村上覚史. ダイレクト PCR法による牛白血病ウイルスの簡易同定法の開発と、本法を用いた疫学調査. 山口獣医学雑誌 43 号21-27

2015

Sato K, Kobayashi T, Misawa N, Yoshikawa R, Takeuchi JS, Miura T, Okamoto M, Yasunaga J, Matsuoka M, Ito M, Miyazawa T, Koyanagi Y. Experimental evaluation of the zoonotic infection potency of simian retrovirus type 4 using humanized mouse model. Scientific Reports 14;5:14040

Takeuchi JS, Ren F, Yoshikawa R, Yamada E, Nakano Y, Kobayashi T, Matsuda K, Izumi T, Misawa N, Shintaku Y, Wetzel K, Collman R, Tanaka H, Hirsch V, Koyanagi Y, and Sato K. Coevolutionary dynamics between tribe Cercopithecini tetherins and their lentiviruses. Scientific Reports 4;5:16021 PubMed

Iwami S, Takeuchi JS, Nakaoka S, Mammano F, Clavel F, Inaba H, Kobayashi T, Misawa N, Aihara K, Koyanagi Y, Sato K. Cell-to-cell infection by HIV contributes over half of virus infection   eLife   4

Sato K, Kobayashi T, Misawa N, Yoshikawa R, Takeuchi JS, Miura T, Okamoto M, Yasunaga J, Matsuoka M, Ito M, Miyazawa T, and Koyanagi Y. Experimental evaluation of the zoonotic infection potency of simian retrovirus type 4 using humanized mouse model. Scientific Reports   14;5:14040

Iwami S, Sato K, Morita S, Inaba H, Kobayashi T, Takeuchi JS, Kimura Y, Misawa N, Ren F, Iwasa Y, Aihara K, Koyanagi Y. Pandemic HIV-1 Vpu overcomes intrinsic herd immunity mediated by tetherin. Scientific Reports   17;5:12256

Ebina H, Kanemura Y, Misawa N, Sakuma T, Kobayashi T, Yamamoto T, Koyanagi Y. A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector. PLoS One   17 ( 10 ) e0120047

2014

Kobayashi T, Koizumi Y, Takeuchi JS, Misawa N, Kimura Y, Morita S, Aihara K, Koyanagi Y, Iwami S, Sato K. Quantification of deaminase activity-dependent and -independent restriction of HIV-1 replication mediated by APOBEC3F and APOBEC3G through experimental-mathematical investigation. Journal of Virology 88(10):5881-7  

Kobayashi T, Takeuchi JS, Ren F, Matsuda K, Sato K, Kimura Y, Misawa N, Yoshikawa R, Nakano Y,   Yamada E, Tanaka H, Hirsch VM, Koyanagi Y. Characterization of red-capped mangabey tetherin: implication for the co-evolution of primates and their lentiviruses. Scientific Reports 2;4:5529